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RNA Interference

New Developments In Dsrna

Recent research has also shown that a class of similar dsRNA fragments, called small temporal RNAs, play important roles in development in the roundworm, fruit fly, and other animals. Although little is so far known about them, these fragments are made by dicer from the cell's own RNA as a normal part of the developmental process and appear to help control gene expression. This is an exception to the statement that the presence of dsRNA signals a threat to the cell; how these are distinguished from threatening dsRNA is not yet known.

Richard Robinson


Ambros, Victor. "Development: Dicing up RNAs." Science 293 (2001): 811-813.

Gura, Trisha. "A Silence that Speaks Volumes." Nature 404 (2000): 804-808.

Lin, Rueyling, and Leon Avery. "RNA Interference. Policing Rogue Genes." Nature 402 (1999): 128-129.

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