RNA Interference
New Developments In Dsrna
Recent research has also shown that a class of similar dsRNA fragments, called small temporal RNAs, play important roles in development in the roundworm, fruit fly, and other animals. Although little is so far known about them, these fragments are made by dicer from the cell's own RNA as a normal part of the developmental process and appear to help control gene expression. This is an exception to the statement that the presence of dsRNA signals a threat to the cell; how these are distinguished from threatening dsRNA is not yet known.
SEE ALSO ANTISENSE NUCLEOTIDES; FRUIT fLY: DROSOPHILA; NUCLEASES; RNA; POST-TRANSLATIONAL CONTROL; RNA PROCESSING; ROUNDWORM: CAENORHABDITIS ELEGANS; TRANSPOSABLE GENETIC ELEMENTS; VIRUS.
Richard Robinson
Bibliography
Ambros, Victor. "Development: Dicing up RNAs." Science 293 (2001): 811-813.
Gura, Trisha. "A Silence that Speaks Volumes." Nature 404 (2000): 804-808.
Lin, Rueyling, and Leon Avery. "RNA Interference. Policing Rogue Genes." Nature 402 (1999): 128-129.
Additional topics
Medicine EncyclopediaGenetics in Medicine - Part 4RNA Interference - Dicing Up Dsrna, Interference, Research Uses Of Rna Interference, New Developments In Dsrna