Triplet Repeat Disease
Classification Of Triplet Repeat Disorders
Triplet repeat disorders fall into two subclasses, depending on the location of the trinucleotide repeat within the gene. The first subclass has triplet repeats occurring in noncoding sequences of DNA, either introns or regions at the start or end of the gene, called 5′ ("five prime") or 3′ ("three prime") untranslated regions. The second subclass is characterized by (CAG)n repeats that code for repeated stretches of the amino acid glutamine (polyglutamine) in coding regions of the affected gene.
- Triplet Repeat Disease - Noncoding Triplet Repeat Disorders
- Triplet Repeat Disease - Implicated In Diseases
- Other Free Encyclopedias
Medicine EncyclopediaGenetics in Medicine - Part 4Triplet Repeat Disease - Implicated In Diseases, Classification Of Triplet Repeat Disorders, Noncoding Triplet Repeat Disorders, Polyglutamine Diseases