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Genetic Susceptibility To Complications

As mentioned above, diabetes is associated with complications involving the eyes, kidneys, blood vessels, and heart. However, not all individuals with diabetes develop these complications. There is increasing evidence that there are genes other than those that increase susceptibility to developing the disease that may influence susceptibility to developing its complications. These genes are not yet identified, but they are likely to interact with other known risk factors for complications, including poor blood-sugar control and increased blood-pressure and blood-cholesterol levels.

Toni I. Pollin

and Alan R. Shuldiner


Internet Resources

American Diabetes Association. <http://www.diabetes.org>.

Joslin Diabetes Center. <http://www.joslin.org>.

Juvenile Diabetes Research Foundation International. <http://www.jdrf.org>.

National Institute of Diabetes and Digestive and Kidney Diseases. <http://www.niddk.nih.gov>.

Online Mendelian Inheritance in Man. Johns Hopkins University, and National Center for Biotechnology Information. <http://www.ncbi.nlm.nih.gov/Omim>.

Additional topics

Medicine EncyclopediaGenetics in Medicine - Part 1Diabetes - Type 1 Diabetes, Type 2 Diabetes, Other Specific Types Of Diabetes, Genetic Susceptibility To Complications - Gestational Diabetes Mellitus