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Combinatorial Chemistry - The Combinatorial Approach, Drug Targets, High-throughput Screening, Selex

Medicine EncyclopediaGenetics in Medicine - Part 1

Combinatorial chemistry is a technology for creating a multitude of different compounds by reacting different combinations of interchangeable chemical "building blocks." The compounds are then screened for their ability to carry out a specified function, most commonly to act as drugs to treat a disease. Combinatorial chemistry allows the rapid synthesis and testing of many related compounds, greatly speeding the pace of drug discovery. Automated synthesis and screening systems are key to this approach.

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