Other Free Encyclopedias » Medicine Encyclopedia » Aging Healthy - Part 2 » Frontotemporal Dementia - The Clinical Syndrome Of Ftd (fld), Primary Progressive Aphasia, Corticobasal Degeneration, Pick Complex

Frontotemporal Dementia - Treatment

clinical neurology kertesz pick clinical

Treatment of FTD is aimed at controlling symptoms pharmacologically. Most of the drugs used were already approved medications, usually used for Parkinson's disease, AD, or depression. Attempts to use levodopa, selegiline, fluoxetine, or similar drugs have not altered the course significantly but may help restless, compulsive, or apathetic behavior. Until proper randomized clinical trials are carried out, these drugs can not be considered efficacious, especially considering the variability and the relatively long clinical course of FTD.

ANDREW KERTESZ

BIBLIOGRAPHY

BRUN, A. "Frontal Lobe Degeneration of Non-Alzheimer Type. I. Neuropathology." Archives of Gerontology and Geriatrics 6 (1987): 193–208.

CONSTANTINIDIS, J.; RICHARD, J.; and TISSOT, R. "Pick's Disease—Histological and Clinical Correlations." European Neurology 11 (1974): 208–217.

HUTTON, M.; LENDON, C. L.; RIZZU, P.; et al. "Association of Missense and 5'-plice-site Mutations in Tau with the Inherited Dementia FTDP-17." Nature 393 (1998): 702–705.

KERTESZ, A.; DAVIDSON, W.; and FOX, H. "Frontal Behavioral Inventory: Diagnostic Criteria for Frontal Lobe Dementia." Canadian Journal of Neurological Sciences 24 (1997): 29–36.

KERTESZ, A.; HUDSON, L.; MACKENZIE, I. R. A.; et al. "The Pathology and Nosology of Primary Progressive Aphasia." Neurology 44 (1994): 2065–2072.

KERTESZ, A.; KAWARAI, T.; ROGAEVA, E.; et al. "Familial Frontotemporal Dementia with Ubiquitin-Positive, Tau-Negative Inclusions." Neurology 54 (2000): 818–827.

KERTESZ, A., and MUNOZ, D. G. Pick's Disease and Pick Complex. New York: Wiley-Liss, Inc., 1998.

The Lund and Manchester Groups. "Clinical and Neuropathological Criteria for Frontotemporal Dementia." Journal of Neurology, Neurosurgery and Psychiatry 57 (1994): 416–418.

MESULAM, M. M. "Slowly Progressive Aphasia without Generalized Dementia." Annals of Neurology 11 (1982): 592–598.

PICK, A. "Über die Beziehungen der senilen Hirnatrophie zur Aphasie." Prager Medizinische Wochenschrift 17 (1892): 165–167.

REBEIZ, J. J.; KOLODNY, E. H.; and RICHARDSON, E. P., JR. "Corticodentatonigral Degeneration with Neuronal Achromasia." Archives of Neurology 18 (1968): 20–33.

SNOWDEN, J. S.; GOULDING, P. J.; and NEARY, D. "Semantic Dementia: A Form of Circumscribed Cerebral Atrophy." Behavioral Neurology 2 (1989): 167–182.

SNOWDEN, J. S.; NEARY, D.; and MANN, D. M. A. Frontotemporal Lobar Degeneration: Frontotemporal Dementia, Progressive Aphasia, Semantic Dementia. London: Churchill Livingstone, 1996. WILHELMSEN, K. "Frontotemporal Dementia is on the MAPt." Annals of Neurology 41 (1997): 139–140.

[back] Frontotemporal Dementia - Neurogenetics

User Comments

The following comments are not guaranteed to be that of a trained medical professional. Please consult your physician for advice.

Your email address will be altered so spam harvesting bots can't read it easily.
Hide my email completely instead?

Cancel or