Frontotemporal Dementia

Pick complex (Kertesz et al., 1994; Kertesz and Munoz) is a unifying concept of the overlapping clinical syndromes of FLD, PPA, CBD, FTD, and associated MND and the underlying neuropathological findings, emphasizing commonalities rather than differences between them. It designates both the pathological and the clinical overlap, avoids the restriction of pathology and clinical symptomatology to the frontotemporal cortex and acknowledges the relationship to PiD. The term frontotemporal degeneration or frontotemporal dementia does not include the frequent subcortical involvement, parietal pathology, and extrapyramidal symptomatology, and is mostly used for the behavioral syndrome.