DNA Vaccines

DNA vaccines represent a new approach to immunization, in that an individual is directly inoculated (injected) with DNA that genetically encodes one or more of the antigens associated with the infectious agent. In effect, the recipient of a DNA vaccine produces the immunizing protein (antigen) within his own cells as a result of the immunization process.

This revolutionary approach to vaccination offers many advantages over conventional vaccines. A major advantage is that DNA vaccination stimulates both the antibody and cell-mediated components of the immune system, whereas conventional protein vaccines usually stimulate only the antibody response. Furthermore, DNA vaccines are simpler to produce and store than conventional vaccines, and are therefore less expensive. Preliminary studies to date indicate that DNA vaccines appear to be very safe and to produce no side effects.