Other Free Encyclopedias » Medicine Encyclopedia » Genetics in Medicine - Part 1 » Cancer - A Genetic Disease, Classification Of Cancer Types, Benign Or Malignant Tumor, Type Of Cell - Type of Tissue, Site of Origin

Cancer - Future Directions In Diagnosis And Treatment

genetic clinical york cell growth specific

The increased knowledge of cancer at the biochemical and genetic level has led to many advances toward better diagnosis and treatment of cancer, including the design of more specific drugs that are less toxic to normal tissue. This includes the use of antisense molecules, which are nucleic acid sequences that are complementary to the mRNA of a target gene. As the two sequences are complementary, they anneal and thus the mRNA is blocked from being translated into a protein, resulting in less of that particular protein being produced (such as growth factor receptors). Drugs specific in blocking angiogenesis are able to control the growth and spread of tumors, especially when used in combination with other treatments.

Giles Watts

Bibliography

Greider, C. W., and E. H. Blackburn. "Telomeres, Telomerase and Cancer." Scientific American 274 (1996): 80-85.

Kiberstis, Paula, and Jean Marx. "The Unstable Path to Cancer." Science 297, no. 5581 (2002): 543.

Lenherd, Raymond E., et al. Clinical Oncology. Atlanta, GA: American Cancer Society, 2001.

Rosenberg, S. A., and B. M. John. The Transformed Cell: Unlocking the Mysteries of Cancer. New York: Putnam, 1992.

Weinberg, R. A. Racing to the Beginning of the Road: The Search for the Origin of Cancer. New York: Putnam, 1998.

Weinberg, R. A. One Renegade Cell: How Cancer Begins. New York: Basic Books, 1999.

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